Intestinal Diseases: IBS, Crohn’s, Colitis
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Gut health
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Gut health
“The nicotinic acid GPR109A receptor regulated the structure of the gut microbiota & that the microbial populations were different between WT and Gpr109a- mice. Bacteroidetes & Firmicutes
These findings indicate that GPR109A regulates the gut microbiota”
https://www.frontiersin.org/articles/10.3389/fimmu.2018.02079/full
frontiersin.org
The intestinal epithelial barrier is important to mucosal immunity, although how it is maintained after damage is unclear. Here, we show that G protein-coupled receptor 109A (GPR109A) supports barrier integrity and decreases mortality in a mouse cecum ligation and puncture … Continue reading
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“Our data reveal that the level of dietary Fe reaching the colon affects the microbiome, and its essential function of providing the host with beneficial butyrate” and the “strong regulatory effect of Fe on gut microbiota butyrate producers and on the concentrations of butyrate, which contributes to the maintenance of host gut health.”
Iron Modulates Butyrate Production by a Child Gut Microbiota In Vitro
https://journals.asm.org/doi/10.1128/mbio.01453-15
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