[AJ West]

…here GPR109A shows improvement in Nrf2 and therefore P-gp. This beneficial effect can be seen throughout the body, as such this paper below is also referenced in the “Cancer” forum for its preventive nature in mastitis which relates to breast cancer:

“GPR109A alleviate mastitis and enhances the blood milk barrier by activating AMPK/Nrf2 and autophagy”

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579459/

ncbi.nlm.nih.gov

GPR109A alleviate mastitis and enhances the blood milk barrier by activating AMPK/Nrf2 and autophagy

Mastitis causes great psychological and physical pain among women. Our previous studies found that niacin has anti-inflammatory effect, and the realization of this function depends on GPR109A. However, there are no previous reports about the anti-inflammatory ...