[AJ West]

“Cryopreservation exposes sperm to physical and chemical stresses causing cell damages and impairs sperm functions.”

Even with this significant damage:

“cryopreservation generated oxidative stress, inducing sperm cryodamage, reducing progressive motility and sperm quality, as an indicator of significant chromatin/DNA damage.”

still,

“nicotinic acid induced a significant improvement in sperm parameters and chromatin quality, compared to control groups (p < 0.05).”

Correlation between sperm motility and sperm chromatin/DNA damage before and after cryopreservation and the effect of folic acid and nicotinic acid on post-thaw sperm quality in normozoospermic men | SpringerLink

link.springer.com

Correlation between sperm motility and sperm chromatin/DNA damage before and after cryopreservation and the effect of folic acid and nicotinic acid on post-thaw sperm quality in normozoospermic men - Cell and Tissue Banking

Cryopreservation exposes sperm to physical and chemical stresses causing cell damages and impairs sperm functions. The aim of this study was to evaluate the association between motility and sperm chromatin/DNA damage before and after cryopreservation and investigate the effects of … Continue reading