[AJ West]

Niacin Inhibits Apoptosis and Rescues Premature Ovarian Failure:

“Over 99% of mouse and human ovarian follicles will undergo specialized cell death including atresia and apoptosis. Reduction of apoptosis may help reduce infertility and maintain the reproductive ability in women.”

“Administration of niacin to treat premature ovarian failure (POF) in mouse models showed inhibition of follicular apoptosis under harmful conditions, such as radiation and chemotherapy damage, by markedly reducing cumulus cell apoptosis.

Additionally, the number of developing follicles increased after administration of niacin.”

Niacin Inhibits Apoptosis and Rescues Premature Ovarian Failure – PubMed (nih.gov)

pubmed.ncbi.nlm.nih.gov

Niacin Inhibits Apoptosis and Rescues Premature Ovarian Failure - PubMed

Niacin may have an important function in treating POF by reducing apoptosis in clinical applications.