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83377 posted an update 6 days ago
Review
Unconventional T cells in anti-cancer immunity.
Laub, A., Rodrigues de Almeida, N., & Huang, S. (2025). Frontiers in immunology, 16, 1618393.
2025 Jul 17
DOI: 10.3389/fimmu.2025.1618393
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83377 posted an update 6 days ago
The molecular basis underpinning the potency and specificity of MAIT cell antigens.
Awad, W., Ler, G.J.M., Xu, W. et al. Nat Immunol 21, 400–411 (2020).
Published 02 March 2020
DOI: 10.1038/s41590-020-0616-6
doi.org
Mucosal-associated invariant T (MAIT) cells recognize vitamin B metabolites presented by the molecule MR1. Rossjohn and colleagues generate multiple altered metabolite ligands and determine their structures in the context of MR1 and the TCR to develop a generalized framework for … Continue reading
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83377 posted an update 6 days ago
Recognition of vitamin B metabolites by mucosal-associated invariant T cells.
Patel, O., Kjer-Nielsen, L., Le Nours, J. et al. Nat Commun 4, 2142 (2013).
Published 11 July 2013
DOI: 10.1038/ncomms3142
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83377 posted an update 6 days ago
Review
Recognition of Vitamin B Precursors and Byproducts by Mucosal Associated Invariant T Cells.
Eckle, S. B., Corbett, A. J., Keller, A. N., Chen, Z., Godfrey, D. I., Liu, L., Mak, J. Y., Fairlie, D. P., Rossjohn, J., & McCluskey, J. (2015). The Journal of biological chemistry, 290(51), 30204–30211.
2015 Dec 18
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83377 posted an update 6 days ago
Microwave Radiation Caused Dynamic Metabolic Fluctuations in the Mammalian Hippocampus.
Xin, Y., Guan, S. T., Ren, K., Wang, H., Dong, J., Wang, H. Y., Zhang, J., Xu, X. P., Yao, B. W., Zhao, L., Shi, C. X., & Peng, R. Y. (2024). Metabolites, 14(7), 354.
2024 Jun 23
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83377 posted an update 6 days ago
Dietary intake of B vitamins and methionine and breast cancer risk.
Bassett, J. K., Baglietto, L., Hodge, A. M., Severi, G., Hopper, J. L., English, D. R., & Giles, G. G. (2013). Cancer causes & control : CCC, 24(8), 1555–1563.
2013 Aug
DOI: 10.1007/s10552-013-0232-y
Conclusions:
We found weak evidence of an inverse association between breast…
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83377 posted an update 6 days ago
Effect of dietary B vitamins on BMD and risk of fracture in elderly men and women: the Rotterdam study.
Yazdanpanah, N., Zillikens, M. C., Rivadeneira, F., de Jong, R., Lindemans, J., Uitterlinden, A. G., Pols, H. A., & van Meurs, J. B. (2007).Bone, 41(6), 987–994.
2007 Dec
DOI: 10.1016/j.bone.2007.08.021
We conclude that increased dietary…
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83377 posted an update a week ago
Cognitive Risks of AI: Literacy, Trust, and Critical Thinking.
Kulal, A. (2025). Journal of Computer Information Systems, 1–13.
Published online: 04 Nov 2025
DOI: 10.1080/08874417.2025.2582050
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athena333 posted an update a week ago
After ~8 months, Jan- Aug, Removing the Vitamin C allowed my shoulder to heal
It took about a month to FINALLY get my shoulder healed.
By just stopping the Vitamin C and using
Niacin + L Tryptophan in proper proportions.
I always thought Vitamin C was the super vitamin but in the case of my shoulder — which I injured by moving a monitor and a printer around.Thank you, Dr Kats for figuring this out!
I never would…
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Maybe it is Vitamin C, and you’re seeing the results just now, coincides with stopping it !!!
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Ascorbic acid looks like a “super vitamin” ONLY because it forces the ONLY remaining NAD⁺-producing pathway — kynurenine — to run faster, by reducing iron and enabling tryptophan catabolism, generating just enough NAD⁺ to keep a dying system limping along.
Let’s walk through this step by step.
—
1. When nicotinic acid is absent, the body has…
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a week ago (edited)
Randomized Controlled Trial
Riboflavin as an independent and accurate biomarker for adherence in a randomized double-blind and placebo-controlled clinical trial.
Ramanujam, V. S., Nayeem, F., Anderson, K. E., Kuo, Y. F., Chen, N. W., Ju, H., & Lu, L. W. (2017). Biomarkers : biochemical indicators of exposure, response, and…
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