• My 9 yo female black labrador retriever (72 lbs) is showing her age this year. She has an increasing amount of fatty lumps, some of which are in places that must make her uncomfortable.

      She was crated when she was young, so takes solace in confined places. If our overly sensitive smoke alarm in the kitchen goes off, she runs for a hiding place (usually upstairs under someone’s bed) and has to be coaxed out. Same for if someone is yelling for any reason or loud noises of any kind; she responds the same way.
      I have tried introducing the protocol with her but she seems to freak out a bit with the flush. If she can taste it, she quits eating. I suspect she may have made the association between the flavor and the flush.
      She now goes off to hide when she flushes. Ugh! So, I’ve gotten away from giving it to her because when the family sees her response to it, they think it isn’t fair because she can’t understand. My family all takes the protocol and understands that it gets better as you go, but they sympathize (a bit too much) with the dog. My thoughts are that she’ll get over it and feel great soon enough. But I digress….

      In the last few days she’s been suffering with a respiratory infection that seems to be clearing itself, but it is an excellent reminder that she could use the benefits of the protocol.
      So, with the final version of the protocol, I am looking for a bit of help to administer this properly. If I start her at 50% of an adult starting dose (say, 500 mg) would that be okay? Should we go less or more to start?
      I want to get her up to a good therapeutic dose quickly, within a week if she were a human.
      Maybe I should try to get her out for a walk/active for when the flush might hit as a distraction?
      Any insight or experiences shared will be appreciated!
      Also, I’ve searched in the STUDI3S group for “lipoma” and don’t see anything. Is there any research available about resolution of benign lipomas with any/all of the components of the protocol (human or canine)?

      Thank you so much in advance. I want to make this as comfortable as possible for her while realizing all of the gains to be had from supplementing her.

      • That is great news! Thank you for the insight on her dosing. The lipomas on my dog are forming in her armpits, which I believe make her uncomfortable. At the vet, they are quite sure that they are nothing more than a fatty tumor.

        • I apologize for just seeing this. Has been an extremely busy past few days/weeks. Nevertheless, I am sad to hear about your pup, but there is good news. I do think they will adapt just fine to the GPR109A.com product (assuming you are using ALL three per the ratio as disseminated in HOM3OSTASIS.com/Protocol (i.e., flush niacin, acetylglutamine, and folic acid in specific ratio together)). The GPR109A product provides them perfectly fused in the ratio and in a compact punch (where taking out contents from just 2 caps would provide this 500 g flush niacin anchor dose). I think this is solid to start at indeed (along with according N-acetylglutamine (i.e., 0.765 g) + folic acid (i.e., 0.61 mcg = MICROgrams (where 1000 mcg = 1 mg), or on the digital precision scale in grams as 0.006 g .

          ^ If you have the individual powders of the three, it would be best to get a little bit of clean water (maybe not even an ounce) and after weighing the three nutrients, put them together and dump into a little eating bowl for wet food as you pour that little bit of water in too. Mix good until you can’t see/sense the powder nutrients having been mixed into there at all. Maybe even add a bit of dry food on top to entice more.

          ^ Alternatively, you can perform the exact same method with powders but without the weighing and instead just opening up the ends of the two capsules into the wet food with a bit of water and mix in inconspicuously etc.

          The dog should not have any issues with the flush really, but what would be my best guess is still perhaps too little dose to get things going more smoothly, however, I am not sure if you are combining flush niacin with acetylglutamine and folic acid as per the HOM3OSTASIS.com/Protocol outlined (or if you have GPR109A.com yet). If no to both these, then there you go (while still I think the dog can benefit with a bit higher even 750 mg flush niacin anchor to start, and go up by 250 mg flush niacin anchor titrations to evaluate forward every two doses or so (try this at least once a day; better a bigger dose once vs. two smaller trying to sneak in). The folic and acetylglutamine in precise ratio with the flush niacin are key to not just empowering flush niacin but smoothening it too from the get-go (along with sufficient dose, and really we can’t go too high, but we want to not make the food too noticeably supplemented to the dog, if doses beyond like 3 grams, which I doubt they will need).

          I would go up dose here to 1 even 2 grams flush niacin anchor, and also perform topical (use 6 g N anchor dissolved into ~8 oz water like you’re gonna take oral dose but put in spray bottle to spray ~3″ from the region(s) on-spot and let seep in best.

          How are you making the doses?

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