The former is correct. And moreover, vitamin A is not really a vitamin so no need for it. If you think you need A, that’s a niacin and tryptophan deficiency

Dr. Kats—Does niacin dosing satisfy bodily requirements for Vitamin A, or should one supplement with it?

Hello Dr. Kats—Just logged on after a hiatus of several months to find your thorough summary of research on the question of tinnitis. Thank you so much!

Hello Group.

I wanted to know more about your personal and subjective experiences using NAT Acids. 😄

Gonna hunt down the full soon:

Nicotinic acid treatment of tinnitus; a clinical; audiological examination

https://pubmed.ncbi.nlm.nih.gov/13227997/

And another one:

Relationship Between Diet and Tinnitus: Korea National Health and Nutrition Examination Survey

https://e-ceo.org/m/journal/view.php?id=10.21053/ceo.2017.01221

Effect of ascorbic acid on the numerical hair cell loss in noise exposed guinea pigs
https://www.sciencedirect.com/science/article/abs/pii/0378595588900263 [full text PDF attached]

Treatment of deafness

https://www.periodicos.capes.gov.br/index.php/acervo/buscador.html?task=detalhes&id=W2033095037

Full text here: https://sci-hub.ru/10.1288/00005537-194008000-00006

I ran into the below paper across my re-review of my literature review on this topic:

MÉNIÈRE’S SYMPTOM COMPLEX

Its Relation to Chemistry; an Etiologic Study

GRANT SELFRIDGE, M.D.

https://jamanetwork.com/journals/jamaotolaryngology/article-abstract/585241

^ Full text attached as PDF to this message below…

I have copy-pasted the most important…

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Krehl observed that adding ascorbic acid to a high-protein diet [i.e., one highest in tryptophan] caused a rapid weight gain in female control animals.

The Relation of Diet Composition and Vitamin C to Vitamin A Deficiency: One Figure

Yale Nutrition Laboratory, Department of Physiological Chemistry,

Yale University School of Medicine, New…

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“Six proposed COVID‐19 therapeutics were identified as possessing ototoxic side effects including chloroquine and hydroxychloroquine, azithromycin, lopinavir‐ritonavir, interferon, ribavirin, and ivermectin.”

“Many previously or currently used COVID‐19 therapeutics have known ototoxicity including antimalarials, macrolide antibiotics,…

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Thank you, Dr. Kats, for your detailed explanation as well as encouragement!

Please forget about NAG … and I am not sure what “Niacin” you are referring to, if it is coming from PureBunk like the NAG was… it is the wisest decision you have ever made in your life you will see getting the real niacin and vitamin C that I am packing now… It is finally real niacin and niacin’s wife (what we needed the whole time with…

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Dr. Kats, In reading through your insights in this forum regarding tinnitus, as well as the protocols for helping to reduce symptoms, I wonder whether new research has emerged regarding the use of Niacin/Vitamin C in helping to eliminate tinnitus (or should we sufferers continue with Niacin/NAG). I came down with pulsatile tinnitus (sounds…

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Thank you Dmitry. I still have pure bulk niacin powder and will use it today with Swanson iron capsule. Will I need to take folic acid too?

So which dose ratio are you doing exactly of the GPR109A capsules to Swanson iron citrate capsules (assuming you have this Swanson iron citrate: https://www.swansonvitamins.com/p/swanson-premium-iron-citrate-25-mg-60-veg-caps)? It looks to be best at 5 GPR109A Capsules (which is 1,250 mg or 1.25 g flush niacin worth) with every 1 Swanson…

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Yes, exactly – this would be the most efficient method if you have the PureBulk bovine gelatin capsules, which are literally the powders in the simple capsule that allows it to be released with no microcrystalls like the veggie cellulose capsules… I have this noted on the left side of

Protocol

that we can just…

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Also as a follow up please. Do you see any reason why I simply can’t open up the cap and place the niacin directly in some distilled water and stir it, thus eliminating the cap? I did that this morning and the flush was faster and I feel better about not digesting the cap. Am I thinking about this right?

I thank you so very much. Yes, I have been taking regular glutamine not the one you suggest, so I just corrected that. Yes, I would love to be in any group chats however I only have a cell number or email at this time. I find this so fascinating and helpful. I have listened to all your podcasts that I can find.

Excellent! So at least for some, niacin and with the acetylated form, glutamine, are now packing a mighty punch

I am dosing at 1N/1.5AceG for now and I’m good with it so far only 3 days in. But yeah! No tinnitus spikes or any insufferable ringing all day today.

I’m going to stay at this dose until I “feel” like I might want/ need more😊

So you are trying to chase the niacin to do more, however, at this stage of not addressing the niacin deficiency until a certain point, niacin became underpowered to get into cells more and do more therapy as you want until the proper l-glutamine (which originally we figured the free form l-glutamine would readily suffice, but it turns out…

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Very nice! These issues with free l-glutamine were from it not being there with niacin given free l-glutamine’s heat lability and probably also because n-acetyl-l-glutamine IS the meant glutamine to supplement too… curious – did you find any specific dosing level of flush niacin + l-acetyl-l-glutamine that has been the call-it “sweet spot” for you yet?

So I have tinnitus as well which was not caused by injury as I’ve had it for over 20 years to varying degrees… I did notice that it did seem to spike a bit on the glutamine over the last couple months since I started. However, the AceG seems to be working differently now as I’ve noticed a significant reduction in the last couple days since…

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Have loved my response to flushing Niacin. Many Many benefits that I have documented. I have faithfully consumed between 500mg -1000 mg daily with documented reduction in cholesterol. I have used for about 3 months and have had blood drawn three times. Each time my eosinophils have risen. The range is up to 500 for most labs and I am now…

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Ah yes, okay, I saw in Telegram…

So check out this paper:

Nicotinic acid treatment of tinnitus; a clinical; audiological examination
https://sci-hub.ru/10.3109/00016485409123998

^ As you will see, the results with nicotinic acid, alone, and across various kind of subtypes of tinnitus, is variable – some good (notice it was not immediate…

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Certainly … before I divulge further, have you acquired/evaluated N-acetyl-L-Glutamine yet?

Further… attached is a very nice book written by this Dr. Parsons going over flush niacin’s causal application to cholesterol modification:

This is easy work for flush niacin (especially with equimolar N-acetyl-L-glutamine to boot) per

Protocol

:

“This meta-analysis involved 2,110 patients with T2DM from 8 RCTs across a wide range of patients’ characteristics. The results of this study suggested that niacin supplementation significantly reduced TC, TG, &…

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This is the easiest thing flush niacin does like clockwork, no questions asked, proved in countless trials… do you mean low HDL- cholesterol?

Yes, all of the iron mishap is typical of the over-aging anemia-like features that develop as flush niacin (and with this, folates, which are made by flush niacin’s NAD+ and in fact l-glutamine catalyzing this final conversion of niacin to NAD+) grows undersupplied (from diet) over the life course (and especially exasperated over COVID days).…

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Hi Jeanette, I’ll share some things that I read, and hopefully Dmitry will comment on whether the following is right or wrong or somewhere in between: I’ve read that if a person has low iron in the blood, it is likely that they have high-unbound iron in the tissues, organs, etc. In which case, the type of testing for iron reveals a…

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They are not understanding the full mechanisms… and the clearance of it out… or the interplay of glutamine … I have a discussion on this here, if you would like to check it out:

https://www.hom3ostasis.com/groups/gout-uric-acid/forum/discussion/gout-try-try-again/

Dmitry, there’s an odd statement a couple paragraphs before the Conclusion in the posted case study. It says, “. Nicotinic acid decreases the excretion of uric acid. For this reason, I suggested that it be tried for the treatment of gout, but no trials have as yet been reported.“

That doesn’t square with my experience as I’ve taken up to…

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Ah, I forgot to link the paper (which is now linked below):

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1831040/

Before this last smaller dose, when was the last time you took a relatively larger sized (e.g., beyond 1.5 g) dose?

The levels you are at are going to be good but still you will see you should respond to higher ones (but let them…

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Yes, this is typical not necessarily just “detox” but niacin.glutamine trying to repair too – you are accumulating more niacin.glutamine to get things going but still not enough juice. For instance, look at how much niacin (ignore niacinamide) Hoffer reported some patients with arthritis had to take – essentially all higher than the levels…

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THE DISTILLED, CLEAN AS POSSIBLE, COLDISH WATER (H20) IS GOING TO BE HUUUUUGE FOR SMOOTHNESS AND EFFICIENCY, I DO BELIEVE … and on this note … to update:

the molar to mass ratio of the three together, flush niacin : glutamine : water would lead to one as so:
For every 1 gram flush niacin, 1.187 grams glutamine, and 5 oz of water

@sandyriv – good to hear that the second one was much relatively calmer and hopefully calm in general. Now imagine that first dose being 5x call-it “worse” had you done the traditional 500-600 mg dose… I do believe these first reactions even if 5x higher, i.e. at more needed levels to get the show on the road going, have a lot to do with…

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Awesome!!! 🥰

I made this a couple days ago. Been thinking about this scene ever since my first dose. Lol!!! 🤣😂

I hope it uploads ok.

The first dose I took was a lot like yours Sandy. I was like holy fuck!! I’m glad I knew to expect a flushing but I had no idea it would be that intense. But yes each subsequent dose the flush minimizes even to the point if not feeling it at all. Which you’ll kinda miss it. I’ve been on the protocol for 2 mo. today. I am liking it very much…

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My first one I shivered violently for over an hr. My next does 3 days later I had the red flush all over but other than that felt great. The only reason I waited 3 days between is I had grandkids & that really freaked me out. But I’ve been doing it every day since and it’s just gotten better and better. My highest dose so far has been…

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Good job! How much did you do? And YES each one after this will get smoother & smoother.

I didn’t get a headache, but I went up gradually, starting at like 300/360 and upping it by around 200mg per day, and then I jumped from 2000/2400 up to where I’m at now which is 3000/3600 daily. I’m not saying one needs to go that gradually, but I figured it would be good to give my body more time to adjust. That was my intuition for…

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Hi Sandy, the protocol is to dissolve the niacin and glutamine together in the same glass of water and stir. I think a milligram measuring scale is pretty essential for this protocol because as you go up in dose then you have to keep the amount of glutamine as niacin amount x’s 1.2. So for example if you start at 500 mg niacin then you want…

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Very nice – do you have the glutamine though also? I only see flush niacin! And these are the bovine gelatin capsules of it? And yes – for now, it would be best to get a distilled water from the store (try to zone in on one that is going to expire last as it will be the freshest and least exposed to light/heat)… you can swallow the capsules…

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Hi Sandy,

All the ratio amounts are explained nicely on the protocol page…

2.5 grams niacin is 5 caps and 3 grams glutamine is 6 caps. This is ideal especially if you don’t have a scale. For me personally I have found this amount to be good and sounds like in your case it would great to start even taking 2-3 x a day. Definitely take with some…

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No problem! Enjoy our Q&A tonight at 6 PM EST USA

https://www.crowdcast.io/e/LiveQandA/15

Yes, that was it. I logged out of the Crowdcast app, clicked on the link in the email notification and everything worked as it should.

Thank you.