Dr.Kats
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Dr.Kats posted an update 5 weeks ago
JUST PUBLISHED
“milk tryptophan content and availability decrease among WLWH, which may indicate perturbations in milk tryptophan catabolism”
Altered milk tryptophan and tryptophan metabolites in women living with HIV
https://www.nature.com/articles/s41467-025-64566-w
nature.com
Altered milk tryptophan and tryptophan metabolites in women living with HIV - Nature Communications
Children born to women living with HIV suffer increased morbidity and, in low-income settings, have two to three times the mortality of infants born to women without HIV. Here, we profile the milk metabolome of 326 women living with and … Continue reading
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Dr.Kats posted an update 5 weeks ago
Another new niacin trial
Targeting cardiovascular and metabolic risk modification in end stage renal disease (ESRD): a randomized controlled clinical trial on niacin’s effects on lipoprotein(a) and biochemical markers in hemodialysis patients
https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1625417/full
frontiersin.org
BackgroundEnd-stage kidney disease (ESRD) patients on dialysis face pronounced cardiovascular and metabolic risks due to disruptions in lipoprotein(a), phosp...
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Dr.Kats posted an update 5 weeks ago
5 weeks ago (edited)
This applies to all other B-vitamins, and to another so-called "vitamin" too...
“Niacin activated genes involved in riboflavin metabolism and flavin synthesis”
Exogenous niacin enhances Cd tolerance in pepper via NADP(H) pool expansion, photosynthetic electron transport recovery and antioxidant system activation
https://www.sciencedirect.com/science/article/pii/S0304423825004868
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“the Cd+NAC1 treatment significantly enhanced the expression level of the gene encoding NAD+ synthase (EC:6.3.1.5). Correspondingly, compared with mono-Cd treatment, the Cd+NAC1 treatment significantly increased the accumulation of nicotinamide adenine dinucleotide (NAD+, NADP+ and NADPH) and its precursor metabolites, including…
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In the riboflavin biosynthesis pathway, Cd and exogenous NAC influenced the expression levels of four enzyme-coding genes involved in the biosynthesis of riboflavin and its derivatives. The genes encoding riboflavin synthase (EC:2.5.1.9), riboflavin kinase (EC:2.7.1.26), FMN hydrolase (EC:3.1.3.102), and tartrate-resistant acid phosphatase type… Read more
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“Vitamin” C:
Niacin treatment up-regulated the expression of these genes and enhanced the accumulation of ascorbate (ASA) and GSH.
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THIS IS A VERY THOROUGH, EXCELLENT STUDY. I highly recommend for ALL to read.
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Clinical Trial
Vitamin C elevates red blood cell glutathione in healthy adults- View 1 reply
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Dr.Kats posted an update 5 weeks ago
Niacin versus osteoarthritis
• Increased niacin intake is linked to reduced knee pain and better function in osteoarthritis (OA) patients.
• Specific subgroups, such as middle-aged individuals, women, and those with certain dietary habits, benefit more from increased niacin consumption.
• Niacin shows promise for enhancing the quality of life in knee OA patients by…
link.springer.com
Background This research investigates the relationship between niacin intake and knee osteoarthritis (OA) severity, focusing on pain and functional ability due to niacin’s role as a NAD(P)+ precursor, promoting cellular energy, and offering anti-inflammatory, analgesic, and antioxidant effects. Methods The … Continue reading
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Dr.Kats posted an update 5 weeks ago
JUST PUBLISHED
Niacin, an active form of vitamin B3, exerts antiviral function by recruiting β-arrestin through GPR109A to activate the phosphorylation of ERK and STAT1 axis
https://journals.asm.org/doi/full/10.1128/jvi.01519-25 -
Dr.Kats posted an update 5 weeks ago
Niacin against CVD per the Medical Level 1A Evidence
Here is a document comprising how flush niacin (immediate release nicotinic acid) fairs against all sorts of cardiovascular diseases, per evidence from double-blinded randomized placebo-controlled human clinical interventional trials as well as meta-analyses of them.
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Note it was for a member worried about specifically recurrent MI (myocardial infarction), but you can switch MI for pretty much every other cardiovascular disease outcome/event such as strokes, heart failure, and aneurysms.
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Dr.Kats posted an update 5 weeks ago
Free-form L-tryptophan
The nature of the stimulation of the growth of Streptococcus
lactis by yeast extract
https://sci-hub.ru/https://www.cambridge.org/core/journals/journal-of-dairy-research/article/abs/the-nature-of-the-stimulation-of-the-growth-of-streptococcus-lactis-by-yeast-extract/4414332BD10C85A1EB243326EBCE9A32#:~:text=https%3A//doi.org,a%20new%20window%5D
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Fraction 3 = huge quantity of total amino acids and peptides (all sorts of building blocks). It gives ~75% of the stimulation.
Fraction 6 = tiny mass, mostly tryptophan, not a mix. It alone gives ~20% of the stimulation.
That means a single amino acid (free tryptophan), in microgram-scale availability, is contributing almost a THIRD of the… Read more -
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Dr.Kats posted an update 5 weeks ago
Why “fast” aka torture + starve yourself when we got NIACIN (https://HOM3OSTASIS.com/InfinaLife). Been saying this… now, it’s further proven in human trials. You’re welcome.
💪
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Here, let ChatGPT5 Pro break it down for you:
https://chatgpt.com/s/t_690427e8e38481919aa692e65e6dcd0e1- View 1 reply
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Dr.Kats posted an update 5 weeks ago
Free-form L-tryptophan IS the "folic acid" precursor needed to make folinic acid
FACTORS AFFECTING THE BIOSYNTHESIS OF FOLINIC ACID BY ESCHERICHIA COLI’
https://journals.asm.org/doi/pdf/10.1128/jb.78.4.488-491.1959
“The best yields of citrovorum factor [aka folinic acid aka leucovorin] were obtained when the medium contained amino acid composition analogous to casein (namely upon the addition of free-form L-tryptophan).…
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Dr.Kats posted an update 6 weeks ago
Back in Action
I have sent out the packages for everyone who has ordered up to this point, which include 2x the amount ordered! You’re welcome. Again – any members who have yet to order InfinaLife can still take advantage of this offer. And early next-week, for when members who have already taken advantage of this deal are ready to order their subsequent…
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Nice set of choppers!
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Teeth look great!
I am loving Infinalife. I feel good, the flush is easy and I am so happy to measure by the spoon and not the scale!
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Great teeth!! – Got the parcel today so will report back soon!
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Parcel arrived late yesterday thankyou !
Likewise will report back, 1st dose gave a big flush woo hoooo !!!!!
Love the fangs Dr Kats
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