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Dr.Kats posted an update
I got a question...
Besides health/wellness, anti-aging, even immortality, what else about niacin/nicotinic acid (+ don’t forget accompanying bit of L-tryptophan) do you find very appealing?
This could be something very appealing about it that hasn’t even crossed your mind until now / something that you haven’t thought of just yet…
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Honestly, the newer ratio (as of the time of this post the 1 Nicotinic acid to 1/51.51 L-Tryptophan) tastes better/no longer bitter than before! 🤷♂️
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@aevum taste is one that I did not expect haha!
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How are you liking everything else about it?
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@Dr.Kats I had been taking it (2 grams Nicotinic and 39 milligrams L-Tryp) once a day for five days now but I haven’t changed much. I am now considering taking 1 g Nicotinic and whatever that is in l-tryp once after every meal due to it seemingly not doing much for me in my weight loss journey. Otherwise it does keep whatever stressors from accumulating in my body though so in that sense it is working well.
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@aevum 💯 % agree, very smooth
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Hi Dymitry, this one is a little deep and on the edge of all your work, but worth a mention, I remember a couple of years back you mentioned in a recording or maybe a study stating that the social decision making of couples increased as a result of the study ? Along those lines.
Reason being, I’m making very big, positive decisions in my life, yes I’ve done alot personal work however, I know Niacin is playing a more significant role in the background and it’s always intrigued me.
Cheers Jim-
@sandra-keightleybigpond-com yes let me link you to that study one sec, and then go over it myself more
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This one:
Plasma acetylcholine and nicotinic acid are correlated with focused preference for photographed females in depressed males: an economic game study
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1. Clean and elegant
Niacin may shape whether your mind can recognize beauty in real, imperfect humanity—or only in unreachable ideals.
2. More poetic
Niacin helps determine whether the world appears beautiful in its ordinary faces, or only in its rare, impossible ones.
3. More philosophical
Adequate niacin may widen perception itself—letting you value the human and imperfect, rather than only the extraordinary and unattainable.
4. More psychological
Niacin may influence whether your brain can appreciate subtle, everyday beauty, or whether it responds only to extremes.
5. Slightly sharper
Niacin may decide if life feels rich in ordinary moments—or if only the unreal, the flawless, the impossible can move you.
6. Minimalist
Niacin helps determine whether the ordinary is enough—or only the extraordinary counts.-
1. Direct and clear
Without niacin, life can feel like a constant chase after something you can never quite reach.
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2. More existential
When niacin is low, the mind drifts toward the unattainable—because the ordinary no longer feels alive enough to hold onto.
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3. Psychological framing
Without niacin, the world becomes polarized: only the impossible feels meaningful, and everything real seems insufficient.
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4. Poetic
A niacin-starved brain longs for what can’t be had, because it loses the ability to be nourished by what already is.
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5. Philosophical
Lack of niacin collapses the spectrum of experience, leaving you reaching for the unreachable because the attainable has gone dim.
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6. Minimalist
Low niacin makes life feel unwinnable.
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What the !
Thankyou for the article can’t wait to read.
Dmitry, do you get the feeling there is a whole new realm to this lol -
@aevum – I can assure you that it is doing more than you think regarding your weight loss given this trial showing how much extra fat (even the subcutaneous fat folks pay for ultrasonic or infrared treatments to lead to relatively meager losses) had to be lost in order for the weight loss and BMI to not change much in total given the massive increases in muscle mass!
Not to mention: “In patients, muscle metabolome shifted toward controls and liver fat decreased even 50%.” Note that for patients in this trial who needed visceral or liver fat losses, even the semi-extended release version enabled so.
Niacin Cures Systemic NAD+ Deficiency and Improves Muscle Performance in Adult-Onset Mitochondrial Myopathy
https://www.sciencedirect.com/science/article/pii/S155041312030190X
A reminder not only that using raw “weight loss” on the surface as the sole metric to assess “weight loss” can be very misleading, how overlooking gains in sheer muscle mass can overpower the arithmetic to make it appear on the surface as if no bad weight was lost in the process and instead even gained (while miss the good muscle weight gained simultaneously), and also how the changes actually most important for your health and not necessarily for your cosmetics (although that too Is provided, just not as readily noticeable as a sarcopenic, unhealthy and unsustainable weight loss) — while not preliminarily obvious to the naked eye — so very much are indeed happening before our eyes and in due time, as the more detrimental fat that had accumulated / remained stubborn through organ/endothelial/epithelial lining gets broken up and cleared more, will only remain and thus then happen in isolation more to soon grow more noticeable. The timing of the transition from more crucial internal to more aesthetic external corporal fat loss ensuing to the point of making it clear to the individual will generally be once the HDL levels get to their max while total cholesterol/bad low-density lipid markers and triglycerides hit their bottom, if you want to really be a thorough accountant here. However, I think it will be much more enjoyable to take a sigh of relief and enjoy life from here, knowing that all the improvements you desire are coming along and simply not possible without niacin (+ L-tryp, which I apologize is likely boosting your muscle mass even more than just niacin would have, in turn inadvertently obfuscating your naked-eye perception into thinking you’re not actually making necessary and massive strides when you absolutely are, and at unfathomable levels without it and niacin supplemented). On a final note, we also have to remember how much sheer metabolic modulation, that is niacin making NAD+ aka proton motive force to counter inflammation and oxidative stress breaking down cells & tissue is always ongoing but here with the free fraction of tryptophan in coupled pair coming alongside, is finally starting to really quell these oxidative free radical propagations which led to waste of tryptophan as fuel for NAD+ and with that, our soft tissue away in lieu of niacin-tryp exogenously incoming before, and so with that, a lot of lost muscle and thus sheer mass (weight) that assuming niacin-tryp supplementation now is regaining immediately at a rate that quantitatively exceeds that of the bad fat weight being reduced which then is not, again on the surface, rightfully calibrated and even realized when assessment then is based strictly on total body mass/weight.
Here are some more relevant papers:
https://www.aidsmap.com/news/feb-2002/niacin-reduces-abdominal-fat-pilot-study (3rd image below)
https://pubmed.ncbi.nlm.nih.gov/30596513/
https://pmc.ncbi.nlm.nih.gov/articles/PMC3742781/
I will be exporting all this info from the herein comment on this thread into a whole new post on our newsfeed, as I imagine other members would find this informative as well!1-
@Dr.Kats Thank you, I will try and read through each every paper and image you’ve sent my way over this weekend while I take like 3g NA and 1/51.51th of that 3g in L-Tryptophan dissolved in distilled water 40 minutes after each meal for the time being.
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