Parkinson’s Disease & Sleep
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Parkinson’s Disease & Sleep
“GPR109A has a high affinity for niacin (also known as vitamin B3 or nicotinic acid) which also acts as its agonists and help suppress inflammation [10], [11].
We propose that GPR109A is a crucial part of the chronic inflammation and microglia activation in PD.”
*see also our “Sleep” group!
journals.plos.org
Upregulation of GPR109A in Parkinson’s Disease
Background Anecdotal animal and human studies have implicated the symptomatic and neuroprotective roles of niacin in Parkinson’s disease (PD). Niacin has a high affinity for GPR109A, an anti-inflammatory receptor. Niacin is also thought to be involved in the regulation of … Continue reading
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