Gout Uric Acid
I’d like to add gout as another area that Dr. Kats can give us advice on. Gout causes problems for a... View more
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I think we should rename group to Gout, Uric Acid, LEAD
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I think we should rename group to Gout, Uric Acid, LEAD
“Among them, lead was the most heavily weighted component (weight = 0.589 for SUA, 0.482 for hyperuricemia, and 0.527 for gout). In addition, restricted cubic spline regression models showed a linear association of lead with SUA, hyperuricemia and gout.”
ASSOCIATIONS OF METAL EXPOSURE WITH HYPERURICEMIA AND GOUT IN GENERAL ADULTS
Zhu, Ling et al in Journal of the American College of Cardiology (2023.03) p. 1720
https://www.sciencedirect.com/science/article/pii/S0735109723021642?via%3Dihub
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“Among them, lead was the most heavily weighted component (weight = 0.589 for SUA, 0.482 for hyperuricemia, and 0.527 for gout). In addition, restricted cubic spline regression models showed a linear association of lead with the prevalence of hyperuricemia and gout.
Conclusion: Our results suggested that blood metal mixtures were positively associated with gout-related outcomes, with the greatest effect coming from lead.”
Associations of metal exposure with hyperuricemia and gout in general adults
Xu, Jing et al in Frontiers in Endocrinology (2022.12)
https://www.frontiersin.org/articles/10.3389/fendo.2022.1052784/full
This certainly explains why niacin + glutamine have to overpower this early at high-dose so clearly now… the lead puts massive strain on the kidneys… niacin+glutamine will overpower it but not at not overpowering doses…
Many of these crazy dermatitis / eczema pellagras, especially in younger chaps, is definitely metals in the air too
any toxins exposed will use up more niacin/glutamine we don’t have
if that makes sense
they have to be limited too
the terrain and whatever the fuck the other theory is called
they’re both intuitive and correct
it’s not hard lol
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1 Reply
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Treating gout with this protocol is an act of faith. There is so much (mis)information on the internet regarding niacin as a cause of gout/hyperuricemia. It’s either misinformation or incomplete information. Taking the N/G leap before my gout symptoms were completely cleared was a very difficult decision for me but I eventually bit the bullet.
As for this research showing an association of metal exposure to the gout condition, it makes me wonder if niacin detoxes metals from the body which then accumulate in the kidneys unless they are overpowered by N/G In other words, an insufficient level of niacin will cause gout in some people with heavy metal loads but these loads can be overpowered by niacin and glutamine.
At any rate, after my 9 day vacation during which I took 2.5 g N/3 g G each day, I’m back up to 2 X 5N/6G daily. Working my way to 2 X 10/12 per day because I still need to detox a lot of crap out.
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