Perfect Pregnancy
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Fertility
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Fertility
Not only does niacin & iron (II) citrate help during pregnancy to protect against birth defects/mutations– it helps maintain fertility beforehand as well:
“the researchers found that when the pregnant mother took vitamin B3, they corrected these mutations. This was seen as a “double breakthrough,” as scientists discovered both a cause and a possible solution. The cause, NAD, and the solution, niacin.”
“In this study, niacin was found to promote ovarian follicle growth, reducing the risk of oocyte apoptosis and overall infertility.3“
“niacin is required to help you maintain optimal health, supporting your fertility”
imprylusa.com
Niacin, also known as vitamin B3, is both made and used by your body to convert food into energy. When it comes to niacin and prenatal health, this vitamin is required to produce Nicotinamide Adenine Dinucleotide (NAD).
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4 Replies
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“Cryopreservation exposes sperm to physical and chemical stresses causing cell damages and impairs sperm functions.”
Even with this significant damage:
“cryopreservation generated oxidative stress, inducing sperm cryodamage, reducing progressive motility and sperm quality, as an indicator of significant chromatin/DNA damage.”
still,
“nicotinic acid induced a significant improvement in sperm parameters and chromatin quality, compared to control groups (p < 0.05).”
link.springer.com
Cryopreservation exposes sperm to physical and chemical stresses causing cell damages and impairs sperm functions. The aim of this study was to evaluate the association between motility and sperm chromatin/DNA damage before and after cryopreservation and investigate the effects of … Continue reading
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Chronic niacin administration ameliorates ovulation, histological changes in the ovary and adiponectin concentrations:
“Polycystic ovary syndrome (PCOS) is one of the most common ovarian diseases among women of reproductive age.”
“Niacin reduced the bodyweight gain and increased ovary weights in PCOS rats. Niacin also increased the number of normal antral follicles and corpora lutea while reducing the number of cystic follicles and the thickness of theca interna.”
“this study indicates that niacin reduces cystic follicles and improves ovulation in PCOS rats.”
pubmed.ncbi.nlm.nih.gov
Polycystic ovary syndrome (PCOS) is one of the most common ovarian diseases among women of reproductive age. The reproductive and metabolic traits of PCOS are underpinned by adipocyte dysfunction, especially diminished adiponectin secretion. Based on evidence that niacin stimulates adiponectin … Continue reading
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Niacin Inhibits Apoptosis and Rescues Premature Ovarian Failure:
“Over 99% of mouse and human ovarian follicles will undergo specialized cell death including atresia and apoptosis. Reduction of apoptosis may help reduce infertility and maintain the reproductive ability in women.”
“Administration of niacin to treat premature ovarian failure (POF) in mouse models showed inhibition of follicular apoptosis under harmful conditions, such as radiation and chemotherapy damage, by markedly reducing cumulus cell apoptosis.
Additionally, the number of developing follicles increased after administration of niacin.”
Niacin Inhibits Apoptosis and Rescues Premature Ovarian Failure – PubMed (nih.gov)
pubmed.ncbi.nlm.nih.gov
Niacin Inhibits Apoptosis and Rescues Premature Ovarian Failure - PubMed
Niacin may have an important function in treating POF by reducing apoptosis in clinical applications.
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“Reactive oxygen species (ROS) are of the most important detrimental factors on sperm quality during freezing process, which increases the lipid peroxidation (LPO) of cell membranes.”
As mentioned in previous comment above, niacin improves sperm quality after cryoperservation, but also:
” reduces the level of MDA and LPO of sperm membrane during freezing process, and thereby maintains the fertility potential in men with oligospermia.”
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